To date, there is no vaccine or specific therapy against ciguatera . Symptomatic treatment remains the cornerstone of care for intoxicated people.
The advancement of knowledge in toxicology and ethnobotany has opened up serious avenues for future specific treatments. Several compounds capable of specifically countering the action of ciguatoxins have also been identified (brévénal, monoclonal antibodies, rosmarinic acid, etc.). However, if these leads seem to offer for the first time the prospect of targeted and effective treatments, many additional studies must be carried out before they can be considered to be marketed.
Today, the best known treatment against ciguatera lies in “ preventive actions” which primarily involve combined information / education actions, actions to protect coral reefs, integrated management and reinforcement of traceability. fishing sectors of lagoon, surveillance of algal blooms (HABs) of Health Watch, etc .
IMPORTANT
The therapeutic protocols and drugs proposed below for the treatment of ciguatera, are extracted from medical and scientific bibliographic research compiled.
in the books and articles below:
Jérémie Bouchut , “ New developments in ciguatera: study of serious risk factors among a Polynesian hospital cohort and consequences on management in a primary health care structure ”, medical thesis, University of Bordeaux II, 2014. Thesis director : Dr E. Oehler.
Patrick Ly , “ La Ciguatéra in French Polynesia; foundations of traditional treatments and comparison with conventional therapy ”, Pharmacy thesis, University Bordeaux II, 2006. Thesis supervisor: Professor E. Creppy.
Shilpa Kumar-Roiné et al . “C iguatera fish poisoning and other seafood intoxication syndromes: A revisit and a review of the existing treatments employed in ciguatera fish poisoning”, 2010 The South Pacific Journal of Natural and Applied Sciences, 28, 1-26.
Shilpa Kumar-Roiné et al . “A Review of Traditional Remedies of Ciguatera Fish Poisoning in the Pacific”, 2011. Phytother Res. 2011 Jul; 25 (7): 947-58. Pubmed link